When sexual stimulation occurs, nitric oxide is released in the body, which stimulates the production of cGMP (cyclic guanosine monophosphate). Sildenafil inhibits the enzyme phosphodiesterase type 5 (PDE5), which breaks down cGMP. By inhibiting PDE5, Penegra 50 mg helps to increase levels of cGMP, leading to relaxation of the blood vessels in the penis and improved blood flow, thereby facilitating an erection.
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