Developmental and Epileptic Encephalopathies
Developmental and Epileptic Encephalopathies (DEE) comprise a group of severe epileptic disorders characterized by both frequent, often drug-resistant seizures and significant developmental impairment. The term “encephalopathy” in this context refers to marked delays in developmental milestones or, in some cases, loss of previously acquired skills.
DEE syndromes typically begin in the neonatal period, infancy, or early childhood and include: early myoclonic encephalopathy, Ohtahara syndrome, West syndrome, Dravet syndrome (severe myoclonic epilepsy of infancy), Lennox–Gastaut
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